Antibody Analytical Services & Process Development
Antibody Analytical Services
TMT has established a comprehensive analytical platform for antibody drugs to ensure every target is thoroughly evaluated. Our capabilities include purity/impurity analysis, amino acid sequencing, structural characterization, and physicochemical property assessment. With extensive experience, our expert analytical team also provides customized method development tailored to various types of biologics.
Analytical Capabilities:
- Antibody Purity Analysis
- SEC-HPLC
- High / Low Molecular Weight Species (HMW/LMW)
- Monomer Content
- Light / Heavy Chain Identification
- Intact Mass & Variant Characterization
- Intact Protein Mass Analysis
- Major Glycoform Profiling (e.g., G0F / G1F / G2F)
- C-terminal Lysine Heterogeneity
- Post-Translational Modification (PTM) Analysis
- PTM Profiling
- Disulfide Bond Mapping
- Charge Heterogeneity Analysis
- Cation Exchange Chromatography (CIEX-HPLC)
- Acidic / Basic Isoform Profiling
- Peptide Mapping & Sequencing
- Amino Acid Sequence Verification
- Peptide Mapping (LC-MS/MS)
Antibody Process Development
We provide a one-sop solution for antibody production, covering the entire workflow from stable cell line construction and process development to small-scale manufacturing. Leveraging our advanced in-house equipment and rigorous Quality Control (QC), we deliver high-quality, customized antibodies to meet diverse R&D requirements.
Our Workflow:
- Cell Line Development (CLD)
- Process Development & Production
